Hypnotherapy: The Art and Science of Transformational Healing is a comprehensive, evidence-informed exploration of clinical hypnotherapy, integrating its ancient roots with modern physiological science and neuroscience. Beginning by addressing what hypnosis truly is, and importantly what it is not, the book debunks common myths while offering a clear, accessible understanding of hypnosis as a natural, focused state of consciousness. Readers are guided through the rich history of hypnosis, from ancient ritual practices to its evolving role in contemporary therapeutic and medical settings. Central to the book is an exploration of stress as a silent burden on modern health, followed by an in-depth examination of the brain in trance. Drawing on current neuroscience, the text explains the specific brain processes involved in hypnosis, including attention, perception, emotional regulation, and neuroplastic change. The emerging sciences of bioplasticity and epigenetics are explored, highlighting how environment, belief, and experience can influence gene expression and healing. The book delves into the transformative power of feeling, suggestion, repetition, metaphor, and therapeutic language, demonstrating how carefully constructed communication can bypass the conscious critical mind and facilitate meaningful change. Practical insight is offered into self-hypnosis, regression therapy, and the ethical integration of hypnotherapy alongside other therapeutic approaches. Clinical applications are explored across a wide range of presentations, including stress and anxiety, depression, insomnia, pain management, irritable bowel syndrome, trauma and PTSD, phobias, self-esteem, performance enhancement, infertility, autoimmune and inflammatory conditions, and functional neurological disorders. Special attention is given to working with children and supporting neurophysiological healing. Concluding with a reflection on the growing global integration of hypnotherapy within medical and multidisciplinary settings, this book positions hypnotherapy as both an art and a science, grounded in evidence, guided by compassion, and focused on empowering individuals to reclaim agency, resilience, and wellbeing. Written for practitioners, students, and informed readers alike, Hypnotherapy: The Art and Science of Transformational Healing offers a thoughtful, evidence-informed, inspiring contribution to the future of therapeutic practice.